Single Cell Proteomics

Understanding complex processes in heterogeneous tissues lies at the heart of modern biology. The ability to identify cell sub-populations and their state and to characterize their function is leading to breakthroughs in basic analysis, translational research and drug development.  Single-cell protein analysis by mass cytometry enables the most comprehensive profiling of cell surface and intracellular protein markers. Using highly specific metal-conjugated antibodies, a system and optimized data analysis and visualization tools, it is now possible to perform single-tube mass cytometry experiments to produce data on phenotype, signalling state, transcription factors, cytokine, chemokine and growth factor expression, proliferation and cell cycle status and cell health and viability.

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