Norgen Biotek’s Magnetic Bead-Based Total RNA Purification Kit is now fully automated, making high-throughput RNA extraction faster, more reliable, and easier to scale.

Designed to isolate all RNA sizes – including microRNA and small RNA – with exceptional purity and reproducibility, this kit delivers consistent performance across a wide range of sample types. Whether you’re working with tissues, cells, bacteria, viruses, bodily fluids, plants or fungi, Norgen Biotek’s advanced RNA purification technology ensures high-yield results without compromising quality.

Manual RNA extraction can be labour-intensive and prone to variability. Norgen Biotek’s magnetic bead-based kit streamlines the process, reducing hands-on time to just 15 minutes, while enhancing consistency across runs.

This kit is fully compatible with leading lab automation platforms, including:

• Opentrons Flex – a modular and cost-effective automation system designed to scale with your lab.

• Tecan

• Thermo Fisher KingFisher

• Hamilton

• IsoPure

Seamless integration allows labs to boost throughput, minimise human error, and free up valuable time for high-value analysis and discovery.

✅ Compatible with a broad range of sample types
✅ High-quality RNA including microRNA and small RNA
✅ Automation-ready for reliable scalability
✅ Reduced hands-on time and increased reproducibility

Explore how Norgen Biotek and Opentrons can modernise your lab’s RNA extraction today or contact Narisa Dawar our Norgen Biotek Product Manager – ndawar@mscience.com.au.

When it comes to long-read sequencing, high-molecular-weight (HMW) DNA extraction is a critical first step. Poor quality or fragmented DNA can compromise data accuracy, yield, and throughput. That’s why researchers around the world trust PacBio’s Nanobind kits – a next-generation solution for extracting ultra-pure, ultra-long DNA from a wide variety of sample types.

PacBio’s Nanobind technology features a novel magnetic disk with a micro- and nanostructured silica surface. This unique design enables the gentle capture and release of DNA molecules without shearing, preserving fragment lengths of 50 kb to over 300 kb — ideal for HiFi sequencing.

Unlike traditional spin-column methods that can damage DNA, Nanobind allows you to extract DNA with unmatched integrity and purity, ready for PacBio’s long-read workflows.

✅ Ultra-Pure, Long DNA

Nanobind delivers HMW DNA that meets the stringent quality requirements of PacBio HiFi sequencing, enabling better genome assemblies, structural variant detection, and epigenetic analysis.

✅ Broad Sample Compatibility

Whether you’re working with human tissue, plant nuclei, blood, cultured cells, bacteria, or insects, Nanobind kits are designed to handle it all. Options include:

• Nanobind PanDNA Kit (manual)
• Nanobind CBB Big DNA Kit
• Nanobind Tissue Big DNA Kit
• Nanobind Plant Nuclei Big DNA Kit

✅ Automation-Friendly for High Throughput

For labs processing large numbers of samples, Nanobind HT kits are compatible with automation platforms like Hamilton NIMBUS Presto and Thermo Fisher KingFisher. This enables the processing of up to 96 samples in approximately 2.5 hours, reducing labour time and increasing efficiency.

✅ Simple and Scalable Workflow

The protocol follows a straightforward lyse–bind–wash–elute process. With minimal hands-on time, you can reliably extract DNA across projects of any scale.

The PacBio HiFi sequencing platform delivers industry-leading read accuracy and length – but only if it starts with high-quality DNA. Nanobind ensures:

• High yield and purity for confident long-read analysis
• Consistent performance across sample types and conditions
• Optimised workflows for low- and high-throughput labs

Researchers aiming to generate accurate de novo assemblies, uncover structural variants, or explore methylation patterns can depend on Nanobind to deliver the DNA quality required.

Nanobind kits are ideal for a wide range of research applications, including:

• Whole genome sequencing (WGS)
• Structural variant discovery
• Microbiome and metagenomics
• Agricultural genomics
• Rare disease research
• Complex plant and animal genomes

MedChemExpress (MCE) is a supplier of high-quality chemicals, biochemicals and compound libraries, supporting the global scientific research community. MCE’s extensive product portfolio includes a range of screening libraries designed to accelerate drug discovery and development across multiple therapeutic areas. Among these, the Anti-Cancer Compound Library is a powerful tool for researchers seeking targeted solutions and novel cancer therapies.

The library offers over 8,000 compounds with activity against both solid and haematologic tumours, making it suitable for high-throughput screening (HTS) and high-content screening (HCS).

This collection spans key cancer-related pathways such as apoptosis, cell cycle regulation and signal transduction. It also covers diverse signalling pathways — including kinase, GPCR and epigenetics — providing researchers with a comprehensive platform to explore and identify potential anti-cancer agents.

Many of the compounds have undergone rigorous clinical or preclinical evaluations, with some already approved by the FDA, highlighting their therapeutic potential.

The bioactivity and safety profiles of the compounds make the library a useful resource for advancing cancer research. Each compound is also validated for high purity and quality using NMR and LC/MS techniques, which should lead to precise and reproducible results.

A key advantage of MCE’s compound libraries is that users can fully customise a library to meet research needs from the type, quantity and concentrations of compounds and layout, offering the flexibility that researchers need to drive meaningful discoveries in oncology.

Click here to download the MedChemExpress Compounding Libraries brochure or contact Millennium Science at customerservice@mscience.com.au.

The LICORbio Odyssey F Imaging System delivers high sensitivity and broad dynamic range with just a click. Available in 3- and 10-channel models, this advanced platform scans samples up to twice as fast as previous generations, supporting a wide array of applications beyond standard qualitative Western blotting. Whether you’re imaging proteins, nucleic acids, or other biomolecules, the Odyssey F accelerates your workflow without compromising data quality.

Equipped with dual near-infrared (NIR) lasers, the Odyssey F ensures optimal throughput and quantitation for high-quality imaging. In addition, two visible fluorescence lasers unlock powerful multiplexing capabilities, enabling researchers to explore multiple targets simultaneously in plate-based assays, slide imaging, and beyond. This flexibility makes it ideal for researchers aiming to capture more data from a single experiment

Users benefit from rapid scan speeds that reduce total imaging time while improving reproducibility. The Odyssey F is engineered for superior sensitivity and consistent performance, giving researchers increased confidence in their data. Its expanded dynamic range means fewer adjustments and more reliable quantification across a broad concentration spectrum.

Designed for versatility, the Odyssey F supports a wide variety of assays and sample types. The expanded focus offset range ensures compatibility with numerous plate formats and sample depths. Whether you’re conducting EMSA/Gel Shift Assays, In-Cell Westerns, Tissue Section Imaging, or Whole Slide Imaging (WSI), the Odyssey F adapts to your lab’s needs, enhancing both productivity and application reach.

Unchained Labs has raised the bar in biologics characterisation with the launch of Aunty – the world’s fastest and most high-throughput platform for protein stability analysis. Tailored for researchers in biotech, pharma, and gene therapy, Aunty delivers unprecedented speed, sensitivity, and flexibility across a wide range of stability parameters – all from a single 96-well quartz plate.

🔬 Comprehensive Stability Profiling — In Minutes

Aunty characterises protein melting (Tm, Tonset), aggregation (Tagg, Tsize), colloidal stability (kD, B22, G22), long-term stability, and viral vector genome ejection, reading a full 96-well plate every minute. With only 8 µL sample per well, it saves valuable material while delivering maximum insight.

💡 Three Technologies. One Platform.

• Full-Spectrum Fluorescence – For intrinsic or dye-based detection of thermal unfolding.
• Static Light Scattering (SLS) – Detects early-stage aggregation with exceptional sensitivity.
• Dynamic Light Scattering (DLS) – Monitors particle size, polydispersity, and colloidal behaviour.

These modalities can be run in parallel or independently, offering complete flexibility to tailor your assay to the molecule at hand.

1. Thermal Ramp Analysis

Track unfolding and aggregation simultaneously using fluorescence and SLS. Aunty’s sensitivity enables detection down to 25 µg/mL, providing reliable Tm and Tagg measurements across formulations, concentrations, and constructs.

2. Protein and Viral Vector Sizing

Aunty’s ISO-compliant DLS covers particles from 0.3 to 1000 nm. Whether you’re working with therapeutic proteins or viral vectors, it delivers high-precision size measurements and polydispersity profiles in seconds.

3. Colloidal Stability

Quantify aggregation risks under different formulations with Aunty’s automated calculation of kD, B22, and G22. This supports developability assessments for high-concentration biologics and formulation transitions (e.g. IV to SC).

4. Capsid and Genome Stability for AAVs

Using SYBR Gold fluorescence, Aunty detects genome ejection temperatures (Tm) in under an hour. It also pinpoints capsid disruption (Tagg) via SLS – essential for viral vector stability profiling.

5. Isothermal Stability Studies

Run long-term thermal stability tests at set temperatures over hours or days. Monitor changes in unfolding or aggregation over time – with sealed wells for sample integrity and minimal instrument occupation.

At the heart of Aunty is the first 96-well quartz glass consumable – optimised for superior optical clarity, chemical compatibility, and low-volume use. Automation-friendly and easy to seal, it accelerates workflows and minimises contamination risks.

Aunty’s software simplifies complex workflows with easy setup, real-time monitoring, and intuitive visualisation tools. Whether you’re comparing formulations, screening candidates, or optimising viral vector stability, Aunty delivers actionable results – fast.

• Sample Volume: 8 µL
• Read Time: 1 minute for 96 samples
• Temperature Range: 15–95°C
• Light Scattering Sensitivity: Down to 0.05 mg/mL (SLS)
• DLS Range: 0.3–1000 nm
• Genome Ejection Sensitivity: ≥5 × 10¹¹ vg/mL

Whether you’re optimising a therapeutic antibody, screening excipients, or validating AAV vector stability, Aunty is the gold standard in high-throughput protein and viral vector stability characterisation.

For biotech and pharma researchers looking to speed up developability, reduce material usage, and gain multi-parameter insight in a single run – Aunty is the instrument you’ve been waiting for.

The success of high throughput screening (HTS) in finding decent starting points for drug discovery heavily largely depends on the quality of the compound library. MedChemExpress (MCE) can provide 200+ compound libraries which include Bioactive Screening Libraries, Diversity Compound Libraries, High Throughput Screening Libraries, Fragment Libraries and DNA Encoded compound Libraries (DEL). These libraries contain over 16 million available compounds. What’s more, each compound has validated bioactivity data and/or physicochemical properties. These compound libraries are useful professional tools for drug discovery and new indications research and can be used for HTS, high-content screening (HCS) and virtual screening (VS).