Leinco Technologies

Leinco Technologies is a biotechnology company founded in 1992 as a specialty manufacturer of early discovery research products including antibodies, recombinant proteins, ELISA kits, second step reagents and other life sciences products. Shortly thereafter, they also established themselves as a premier provider of custom R&D and manufacturing services focusing on monoclonal antibodies and recombinant proteins.

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Applications

Functional Studies | Flow Cytometry | Western Blotting | Immunohistochemistry | Immunoprecipitation | ELISA | CyTOF® | CODEX®

In Vivo  Functional Grade Antibodies

Leinco's In vivo PLATINUM™ antibodies have the most stringent quality specifications for purity, endotoxins, aggregates and leachable protein A. Each antibody is available in custom concentrations and package sizes. In vivo PLATINUM™ antibodies are also pathogen free and tested by the IDEXX Impact I PCR mouse pathogen profile.

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SARS-CoV-2 (COVID-19)

Leinco Technologies is a leader in the development and manufacturing of antibodies and recombinant proteins for early discovery research and diagnostics. In response to the ongoing worldwide pandemic, Leinco Technologies offers an extensive line of SARS-CoV-2 antibodies and antigens at the highest functional purity levels you have come to know and trust. Leinco's COVID-19 Neutralization MICRO-ELISA and COVID-19 IgG Serology Assay has completed Section IV.D notification process under FDA's "Policy for Coronavirus Disease – 2019 Test During the Public Health Emergency (Revised)" and has not been reviewed by FDA.

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Primary Monoclonal Antibodies

Leinco Technologies manufactures an extensive range of monoclonal antibodies for scientists to assure the level of their research is world class and generates reliable data for publications. Leinco antibodies have the highest purity specifications available in the research products industry and each lot produced is validated for specificity and clone identity. Our data sheets provide relevant clone specific information and application notes for your convenience. We offer antibodies for research in oncology, neuroscience, immunology, apoptosis, signal transduction and many other research areas of interest.

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Polyclonal Antibodies

>1000 Polyclonal antibodies to choose from

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Recombinant Human Biosimilar Antibodies for Research

Leinco Technologies is a leader in the development and manufacturing of recombinant antibodies for early discovery research and diagnostics. We offer an extensive line of recombinant biosimilar antibodies at the In vivo functional purity levels you have come to know and trust from Leinco Technologies. Recombinant biosimilar antibodies are designated for research use only and may not be used for therapeutics. Leinco's biosimilars are made available to researchers to avoid purchasing therapeutic antibodies at pharmaceutical prices for important groundbreaking experiments. Learn more about Leinco's industry leading purity specifications, current product offerings and custom services.

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Recombinant Proteins, Growth Factors & Cytokines

Proteins are the life blood of the world, and Leinco Technologies has built a reputation on being able to provide researchers with biologically active recombinant proteins from a variety of host cells. Leinco often selects mammalian expression systems using Chinese Hamster Ovary (CHO) or Human Embryonic Kidney (HEK) cells as the host to achieve the highest level of biological activity.

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Isotype Control Antibodies

Leinco Technologies manufactures ultra pure isotype control antibodies with the highest purity specifications available for In vivo preclinical studies, diagnostic assay controls or research assay controls. We also offer high purity immunoglobulins, purified from normal animal serum for use in a variety of assay applications. Most of these isotype controls are also offered conjugated to a wide range of fluorescent dyes or enzymes. Click on the learn more tab to see some of the reasons Leinco is the premier supplier of isotype controls for In vivo functional studies.

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Secondary Antibody Products

Leinco Technologies offers a wide range of second step reagents including secondary antibodies, streptavidin and UltraAvidin™, a deglycosylated form of avidin. Leinco then applies its 35 plus years experience in conjugation chemistry to manufacture a wide spectrum of fluorescent and enzyme conjugates for use in a variety of applications such as IHC, fluorescent microscopy, flow cytometry, western blotting, ELISA and other applications.

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CODEX® Barcoded Antibodies

Leinco Technologies manufactures and inventories CODEX® barcoded antibodies and complementary fluorophore-conjugated oligonucleotides (reporter molecules). Providing "Ready to Stain' DNA barcoded antibodies minimizes user optimization for high multiplex imaging. CODEX® can detect over 40 biomarkers in an automated cyclical image acquisition process. Using the fully integrated, high multiplexing CODEX® technology allows an accurate picture of cell neighborhoods and interactions in the tissue microenvironment.

'Ready to Stain' DNA barcoded antibodies are validated according to tissue preparation, such as fresh frozen (FF) or fresh frozen paraffin-embedded (FFPE), and by tissue screened, such as liver, spleen, tonsil, brain, etc. Leinco DNA barcoded antibodies for CODEX® have undergone varying levels of validation and quality testing to assure conjugations are free of unconjugated antibodies and DNA barcodes.

Fluorophore reporter molecules are conjugated to complementary oligonucleotides and matched with barcoded antibodies. The four distinct fluorescent reporter molecules include Alexa Fluor™ 488 (green channel), Alexa Fluor™ 750 (infrared channel), Atto 550 (yellow channel), and Cy5 (bright red channel).

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CODEX® Validated Antibodies

Leinco Technologies offers Purified (CODEX® Ready) antibodies that are 'Ready to Conjugate' to oligonucleotides. These antibodies are formulated in conjugate ready buffers to minimize the antibody preparation needed when performing a CODEX® barcode conjugate. CODEX® Ready antibodies are validated according to tissue preparation, such as fresh frozen (FF) or fresh frozen paraffin-embedded (FFPE), and by tissue screened, such as liver, spleen, tonsil, brain, etc.

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AffiPure™ Purified Immunoglobulins

AffiPure™ control antibody products are produced from normal serum obtained from multiple animal species (Mouse, Rabbit, Rat, etc.) and that have not been previously immunized. This IgG is purified using multiple methods and provided in a standard PBS buffer. This preparation can be used as a control reagent for immunoassays in which the corresponding polyclonal and monoclonal antibodies are used. In addition, Leinco also offers antibody fragments with specific proteases and isotype controls from Mouse, Rat, and other species. Leinco's AffiPure™ proteins are suitable for use as analytes or controls in assays including ELISA, Western Blot, Immunofluorescence Microscopy, and Immunohistochemistry (IHC).

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Streptavidin and UltraAvidin™

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Immune Checkpoints

Leinco Technologies offers a wide range of well known immune checkpoint antibodies and proteins for use in cancer research. Leinco is the premier manufacturer of In vivo functional grade antibodies with the highest purity specifications available. When conducting immune checkpoint preclinical research, it is important to use high purity In vivo grade antibodies to generate reliable data.

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Biological Buffers

Leinco Technologies is a premier manufacturer of bulk and bottled biological buffers. We offer a variety of common in stock packaged biological buffers as well as bulk buffers packaged in bioprocess sterile bags on a custom basis upon request. Leinco's biological buffers have important attributes that make them suitable for use in biological experiments or manufacturing. Please take a moment to click on the learn more button to see why Leinco is a good source for your important biological buffer needs.

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Serum Free Media

Leinco Technologies' AlphaGrow™ SF (Serum Free – No Animal Derived Components) hybridoma cell culture media is a better option in terms of performance and reproducibility to classical cell culture media supplemented with fetal bovine serum for growing hybridoma cell lines in the lab or for large scale production.

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Sheath Fluid & Cytometry Workflow Solutions

Leinco Technologies offers ClearFlow™ Sheath Fluid, ClearSort™ Sorting Solutions, ClearFlow™ Sheath Fluid with a Surfactant, HEPES Buffered Saline for cell sorting, and our PBS formulas which are all isotonic buffered solutions specially formulated to optimally transport cells through the fluidic pathways of instrumentation such as flow cytometers and cell sorters. Because of the complex hydrodynamic focusing technology of the instrumentation and depending on your experimental needs, choosing the correct sheath fluid solution is an important decision for a flow cytometry core manager or lab manager responsible for the optimal performance of their labs instrumentation.

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ELISA Kits

ELISAs have just been made easy. By using Leinco Technologies' ELISA Development Kits, every scientist can ensure accurate research data. We provide all the necessary components to successfully complete your ELISA. All proteins, antibodies, TMB Substrate, and our UltraAvidin™ – HRPO are designed to work together so that you can rely on the results of your assay. We take pride in our products and have always striven to provide the highest quality antibodies and proteins to our customers. We want your research to be successful by using our ELISA Kits and other life science reagents. With Leinco's products you can guarantee your success.

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Apoptosis Detection Kits

Leinco Technologies offers a variety of detection kits and antibodies for studying apoptosis. Leinco manufactures Annexin V reagents and apoptosis kits for flow cytometry. Annexin V is conjugated to either FITC or Dylight™ 650 for emission spectrum flexibility.  Each apoptosis detection kit from Leinco Technologies contains the Annexin V conjugate, propidium iodide and the binding buffer.

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Assay Substrates & Reagents

Leinco Technologies manufactures an assortment of very high quality reagents for immunoassay development including substrates, coating buffers, blocking buffers, wash buffers and stop solutions. Leinco has accumulated a great deal of assay development know-how over the years which can be used to augment the development of your next sandwich ELISA. Contact us so we can make available our assay development expertise or browse the website to see our world class assay development reagents.

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Services

  • Monoclonal Antibody Development
  • In vitro Antibody & Protein Production
  • Antibody Conjugations
  • Assay Services
  • Rapid Expression of Recombinant Antibodies & Proteins
  • Cell Banking, Optimization & Adaptation
  • Antibody & Protein Purification
  • Low Endotoxin Plasmid DNA Preparation
  • Custom Barcoding services by CODEX®

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