Meet EYRA: Multiplexing Reimagined

When it comes to multiplex protein analysis, researchers need accuracy, speed, and simplicity. Traditional flow-based systems have long been the standard, but they bring challenges: sheath fluids, blocked probes, and constant maintenance. Enter the Mabtech EYRA™ – a fluidics-free multiplex immunoassay platform that reimagines how scientists generate cytokine and biomarker data. With confocal imaging, RAWsphere analysis, and compatibility with EYRAplex bead kits, EYRA makes multiplexing faster, simpler, and more reliable.

With EYRAplex magnetic bead assays, EYRA can quantify more than 30 analytes from a single sample – whether that’s serum, plasma, or cell culture supernatant. This means less sample consumption, fewer runs, and richer datasets for every experiment.

At the core of EYRA’s precision is the RAWsphere image analysis algorithm. It identifies each bead, links it to the correct analyte, and quantifies the PE signal with high resolution. Whether you’re measuring six cytokines or a full 30+ panel, RAWsphere ensures your multiplex data is accurate and reproducible.

EYRA is built around a completely flow-free design. No sheath fluid, priming, waste handling or blocked probes.

Instead of pushing samples through fluidics, EYRA uses confocal microscopy to image settled magnetic beads directly in the wells of a 96-well plate. Each bead carries a unique fluorescent dye signature for identification, while analyte-bound PE-labelled antibodies provide the quantitative signal.

The result? You insert your plate, select your assay in the intuitive Mabtech Opal™ software, and hit read. Fifteen minutes later, you have fully processed data – with your samples never leaving the wells.

Opal™ software comes preloaded with templates for every EYRAplex kit. Standards, plate layouts, and gating are handled automatically – so you spend less time setting up and more time on results.

Once the plate read is complete, results are exported directly into Excel, with options for bulk export if you’re working on large studies or multiple plates. No manual reformatting. No data wrangling headaches.

Because EYRA is fluidics-free, there’s no daily calibration or cleaning. No flushing, no wasted consumables, and no time lost to instrument downtime. It’s genuinely a plug-and-play experience – switch it on, run your plate, and walk away with your data.

The Mabtech EYRA isn’t just another multiplex platform – it’s multiplexing reimagined. By removing fluidics and harnessing high-resolution confocal imaging, EYRA delivers:

• High-plex capacity: 30+ analytes per well
• Fast turnaround: ~15 minutes per plate
• No maintenance: no daily cleaning or calibration
• Accurate, reproducible results: powered by RAWsphere analysis

For labs looking to streamline their workflow without sacrificing data quality, EYRA offers a fresh, frustration-free alternative to traditional flow-based systems.

Until next time… happy experimenting!

Joe Roberts, PhD
Product Manager
Millennium Science