10x Genomics Products

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Single Cell Gene Expression

 

Single Cell Immune Profiling

Single Cell Multiome ATAC + Gene Expression

 

Single Cell ATAC

Spatial Gene Expression

 

Instruments

Single Cell Gene Expression

Profile thousands of genes at the single cell level for unbiased characterization of cell types and cell states

  • Combine gene expression analysis with detection of hundreds of cell surface proteins at high resolution for ultra-high parameter multiomic cytometry
  • Use with Targeted Gene Expression panels to focus on the genes and biomarkers most relevant to your research
  • Simultaneously assess CRISPR perturbation phenotypes and gene expression from the same cell to accelerate your functional genomics studies
  • Leverage dual index libraries for reliable sequencing data quality
  • Combine with 3' CellPlex to multiplex up to 12 samples and recover up to 17,500 singlets* per channel, enabling larger-scale single cell studies
  • Singlets are single cells or nuclei captured after multiplet removal.
  • Level up your insights by combining single cell gene expression data with spatial gene expression

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Single Cell Immune Profiling

Profile thousands of genes at the single cell level by barcoding mRNA at the 5' end, for unbiased characterisation of cell types and cell states

  • Simultaneously profile immune repertoire (BCR/TCR) and gene expression from the same cell to enable correlation of clonotype with the corresponding cell subtype
  • Obtain paired, full-length receptor sequences from T cells and/or B cells with complete isotype resolution, providing functional data for antibody/TCR discovery
  • Combine gene expression analysis with detection of hundreds of cell surface proteins at high resolution for ultra-high parameter multiomic cytometry
  • Combine with Targeted Gene Expression Panels to focus on the genes that matter most and accelerate your studies into actionable insights
  • Utilise product partners for Feature Barcode technology (oligo-conjugated antibodies, oligo-conjugated MHCs) to easily perform multiomic profiling
  • Leverage dual index libraries for superior sequencing data quality

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Single Cell Multiome ATAC + Gene Expression

The first commercial single cell multiomics product for simultaneous profiling of gene expression and chromatin landscape at single cell resolution.

Capture multiple measurements simultaneously at the single cell level for deeper characterisation of cell types and states

  • Integrate gene expression with epigenomic landscape through direct measurements from the same cell, eliminating the need for computational inference across datasets
  • Link open chromatin regions and target genes to discover new gene regulatory interactions
  • Obtain multiple measurement types from the same cell to maximize insights from limited samples
  • Take advantage of a simple and robust workflow for straightforward experimental setup
  • Apply easy-to-use data analysis and visualisation software for powerful data interpretation

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Single Cell ATAC

  • Analyse open chromatin regions at single cell resolution, enabling deeper understanding of cellular epigenetic heterogeneity
  • Perform epigenetic profiling for hundreds to tens of thousands of nuclei, enabling detection of rare cells
  • Examine non-coding sequences to discover cisregulatory elements and drivers of gene expression differences between cell types and states
  • Follow a ready-to-use, robust workflow with demonstrated protocols for diverse sample types, including cell lines, primary cells, and fresh and frozen tissue
  • Apply easy-to-use software and visualization tools for straightforward analysis of single cell ATAC data

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Spatial Gene Expression (Visium)

Visualise gene expression within the tissue context.  Available for FFPE and Fresh Frozen samples.

  • Integrate easily with your current laboratory methods and tools for tissue analysis, letting you start your Spatial Gene Expression experiments immediately
  • Avoid the need for dissociating your samples before conducting gene expression studies to retain spatial context
  • Broaden your reach beyond predefined regions of interest to analyse the entire tissue section at once so you don't miss out on unanticipated results
  • Combine with immunofluorescence staining and imaging to gain multiomic characterisation in the spatial context
  • Combine with Targeted Gene Expression Panels to focus on the genes that matter most and accelerate your studies into actionable insights
  • Experience unparalleled insights—full tissue coverage, high resolution, increased sensitivity, and greater depth
  • Visium Cytassist instrument - coming soon!

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Instruments

Whether you're just starting out with single cell, expanding your capabilities, or seeking an automated way to partition individual cells and generate barcoded, sequencing-ready libraries, you're covered. 10x Genomics' proven Next GEM technology provides a trusted path to advance your understanding of cell diversity and function.

Chromium X Series

The most flexible way to single cell.

Expand your single cell capabilities with the most advanced hardware and highest throughput flexibility, enabling multiomic analysis of hundreds to millions of cells.

Chromium Controller

Perform multiomic analysis of hundreds to tens of thousands of single cells with this compact system.

Assay compatibility:

  • Single Cell Gene Expression LT
  • Single Cell Gene Expression
  • Single Cell Immune Profiling
  • Single Cell ATAC
  • Single Cell Multiome ATAC + Gene Expression

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Chromium Connect

Combine single cell partitioning, barcoding, and/or library construction with standardised, automated workflows to maximize your productivity.

  • Obtain consistent and reproducible single cell gene expression libraries
  • Automate your single cell library preparation workflow with maximum walk-away convenience
  • Single cell suspensions to final sequencing-ready libraries
  • Parallel processing between 1 to 8 samples per run

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Visium Cytassist - Coming soon!

Seamlessly transition between standard histology workflows and analyte capture onto Visium slides for in-depth expression analysis.

With Visium CytAssist you can:

  • Study FFPE specimens archived in blocks or on slides
  • Expand ongoing studies of fresh frozen samples
  • Preview tissue section integrity, morphology, and staining patterns
  • Use your slides, annotate your images, choose the best sections
  • Select from powerful spatial expression tools for whole transcriptome, targeted, proteomic, or multiomic studies
  • Quickly and easily capture sample analytes for spatial library creation with Visium Spatial Solutions

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